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Clinical Study on the Detection of Early-Stage Pharyngeal Cancer Using Linked Color Imaging and Blue Light Imaging Technologies with Novel CMOS Endoscopy

Clinical Study on the Detection of Early-Stage Pharyngeal Cancer Using Linked Color Imaging and Blue Light Imaging Technologies with Novel CMOS Endoscopy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111971
Enrollment
Unknown
Registered
2025-11-07
Start date
2025-11-17
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Superficial Squamous Cell Carcinoma of the Pharynx

Interventions

WLI group (White Light Imaging group):using White Light Imaging
BLI group (Blue Light Imaging group):using Blue Light Imaging
LCI group (Linked Color Imaging):using Linked Color Imaging

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 years or older; 2. Histologically confirmed current or previous esophageal squamous cell carcinoma.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to gastroscopy and biopsy; 2. Patients with esophageal squamous cell carcinoma who have received chemotherapy or radiotherapy; 3. Patients with confirmed pharyngeal squamous cell carcinoma; 4. Patients lacking decision-making capacity; 5. Patients who have not signed the informed consent form.

Design outcomes

Primary

MeasureTime frame
Detection rates of neoplastic lesions in the pharynx by WLI, LCI, and BLI;

Secondary

MeasureTime frame
Comparison of the sensitivity (non-inferiority) of BLI (CMOS near-focus) and BLI-ME for detecting neoplastic lesions in the pharynx;Sensitivity and specificity of WLI, LCI, and BLI for detecting neoplastic lesions in the pharyx;

Countries

China

Contacts

Public ContactShi Wang

Zhejiang Cancer Hospital

wangshi@zjcc.org.cn+86 571 88122217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026