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Coagulation Changes in Women with Thalassemia During Pregnancy in South China: A Retrospective Cohort Study

Coagulation Changes in Women with Thalassemia During Pregnancy in South China:A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111964
Enrollment
Unknown
Registered
2025-11-07
Start date
2023-06-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thalassemia

Interventions

Pregnent women in the thalassemia group :None
pregnent women in the non-thalassemia group:None

Sponsors

The First Affiliated Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Singleton pregnancy; 2. Gestational age >= 37 weeks.

Exclusion criteria

Exclusion criteria: 1. Pregnancy with hypertension, hyperlipidemia, cardiovascular and cerebrovascular diseases and other diseases of the hematological system; 2. Pregnancy with diabetes mellitus; 3. Pregnancy with malignant tumor, liver and kidney disease; 4. With personal or family history of thrombosis; 5. Taking drugs that affect coagulation and fibrinolytic system; 6. Long term blood transfusion treatment or blood transfusion before delivery.

Design outcomes

Primary

MeasureTime frame
Activated Partial Thromboplastin Time (APTT);Prothrombin Time (PT); Thrombin Time (TT);Fibrinogen (FIB);International Normalized Ratio (INR);Platelet count (PLT);—

Countries

China

Contacts

Public ContactDong Chaoxuan

The First Affiliated Hospital of Jinan University

cxdong@jnu.edu.cn+86 133 5471 2423

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026