Respiratory weakness
Conditions
Interventions
Nasal high-flow oxygen group:High-flow oxygen through the nose
Sponsors
Beijing Chaoyang Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age 60–100 years, ASA classification II–IV 2. Patients with a Frailty Assessment Score >=1 3. Patients undergoing elective painless ERCP in the ERCP Endoscopy Unit at Beijing Chaoyang Hospital
Exclusion criteria
Exclusion criteria: 1. History of epistaxis, propofol allergy, or contraindications to HFNC (relative contraindications: severe type I respiratory failure; ventilatory dysfunction; pH < 7.30); 2. Paradoxical breathing; 3. Poor airway protection with high risk of aspiration; 4. Haemodynamic instability requiring vasoactive medications; 5. Facial or upper airway surgery precluding HFNC use; 6. Severe nasal obstruction; intolerance to HFNC. 7. Absolute contraindications: cardiac arrest requiring emergency tracheal intubation and invasive mechanical ventilation; 8. Weak spontaneous breathing, coma; extremely severe type I respiratory failure; ventilatory dysfunction with pH < 7.25; inability or refusal to sign informed consent for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of recovery-15; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia;Duration of hypoxemia;Propofol consumption;Recovery time;Hemodynamic changes;Preoperative and postoperative arterial blood gas analysis;Intubation rate;Visual analog scale;Incidence of coughing; | — |
Countries
China
Contacts
Public ContactWang Hui
Beijing Chaoyang Hospital
Outcome results
None listed