Hypertension patients
Conditions
Interventions
propofol group:Administer 0.4 mg/kg of cisatracurium intravenously over 30 seconds. After the patient loses consciousness (BIS value <60), all patients are then admi
Povidone group:Administer 0.4 mg/kg of cisatracurium intravenously over 30 seconds. After the patient loses consciousness (BIS value <60), all patients are then admi
Sponsors
Maternal and Child Health Hospital of Hubei Province
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age 18–80 years; ASA classification II–III; Diagnosed with essential hypertension and receiving regular medication; Scheduled for elective non-cardiac surgery under general anaesthesia; Patient has provided informed consent and signed the consent form.
Exclusion criteria
Exclusion criteria: Individuals with known hypersensitivity to the study drugs (propofol, propofol, soybean, fat emulsion) or their constituents; Severe cardiac insufficiency (NYHA Class III-IV) or significant cardiac arrhythmia; Severe hepatic or renal impairment (Child-Pugh Class C or eGFR < 30 ml/min/1.73m²); Patients with difficult airways or anticipated difficulties with endotracheal intubation; Pregnant or breastfeeding women; Patients who have received sedatives or a2-adrenergic agonists (e.g., dexmedetomidine) within 24 hours prior to enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension during the induction phase;Use of vasoactive drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemodynamic parameters; | — |
Countries
China
Contacts
Public ContactRongrong Yan
Department of Anesthesiology, Maternal and Child Health Hospital of Hubei Province
Outcome results
None listed