Autism spectrum disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Cross-sectional study 1. Admission criteria for normal children: (1) Children aged 1 to 12 with normal development; (2) After a detailed physical examination and mental examination, physical diseases, neurological disorders, mental retardation and pervasive developmental disorders and other mental disorders were ruled out. 2. Inclusion criteria for children with ASD: Children with ASD aged 1-12 In line with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition The Diagnostic criteria for ASD in DSM-5 and the Autism Diagnostic Observation Schedule, Second Edition (ADOS2); Diagnosed with ASD by a deputy chief physician or above in psychiatry or developmental and behavioral pediatrics. And 1-2-year-old infants and toddlers at high risk of ASD or with positive screening results, including those whose older siblings have been diagnosed with ASD or those with positive screening results for ASD risk (meeting the screening positive criteria of the Infant Communication and Symbolic Behavior Development Scale or the Social Attention and Communication Monitoring Checklist). Interventional research 1.Children aged 1 to 12 years with confirmed ASD: They meet the diagnostic criteria for ASD in DSM-5 and ADOS2. b. Diagnosed with ASD by a deputy chief physician or above in psychiatry or developmental and behavioral pediatrics; 2. Failed the mirror self-identification test; 3. Be willing to participate in this project and complete the intervention training within the prescribed time.
Exclusion criteria
Exclusion criteria: Cross-sectional study 1.Subjects suffering from severe respiratory diseases, epilepsy and other organic brain diseases. 2. Children with mental health disorders other than ASD require hospitalization and/or are currently using psychotropic drugs (such as stimulant drugs for ADHD). 3. The child does not meet any of the inclusion criteria. Interventional research 1. Children with mental health disorders other than ASD require hospitalization or hospitalization and/or are currently using mental health Medications (such as stimulants for ADHD). 2. There are abnormalities in vision or hearing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The pass rate of mirror self-recognition test;ASD risk screening indicators;ASD symptom assessment indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective assessment indicators of sleep;Subjective assessment of sleep;Confusion or control factor assessment indicators;Mirror test result;Developmental Assessment Scores (Developmental Age, Full-Scale IQ);Assessment of brain structure and brain development; | — |
Countries
China
Contacts
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine