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Study on the correlation between IL-6 gene polymorphism and the severity of Mycoplasma pneumoniae pneumonia in children in Nanning area

Study on the correlation between IL-6 gene polymorphism and the severity of Mycoplasma pneumoniae pneumonia in children in Nanning area

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111903
Enrollment
Unknown
Registered
2025-11-07
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mycoplasma pneumoniae pneumonia

Interventions

Mycoplasma pneumoniae pneumonia group:None
Normal control group:None

Sponsors

Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 14 Years

Inclusion criteria

Inclusion criteria: In line with the diagnostic criteria of Mycoplasma pneumoniae pneumonia in the ' Expert Consensus on the Diagnosis and Treatment of Mycoplasma Pneumoniae Pneumonia in Children ( 2015 Edition ) ', that is, MPP is mainly manifested by fever and cough. Moderate to high fever is common, and it can also be low fever or no fever. Some children with fever accompanied by chills, headache, chest pain, chest tightness and other symptoms. At the beginning of the disease, most of them had paroxysmal dry cough, a few had sticky sputum, and occasionally had blood in the sputum. The cough would gradually intensify. Some children could have pertussis-like spasmodic cough, and the course of disease could last for 2 weeks or even longer. Most of the children are in good mental condition, without shortness of breath and dyspnea, while the symptoms of infants are relatively severe, and wheezing or dyspnea may occur. The lung moist rales of older children appear relatively late, and there may be signs of pulmonary consolidation.

Exclusion criteria

Exclusion criteria: 1 Basic diseases of the respiratory system : pulmonary tuberculosis, bronchopulmonary dysplasia, congenital malformations of the respiratory tract, lung tumors, bronchiolitis obliterans, airway foreign bodies, ciliary dyskinesia, etc. 2 combined with other pathogens dominant infection and other serious diseases of the system; 3.combined with congenital immunodeficiency, congenital heart disease, malnutrition, congenital genetic metabolic diseases, recent use of immunosuppressive agents.

Design outcomes

Primary

MeasureTime frame
Mycoplasma pneumoniae titer;Mycoplasma pneumoniae nucleic acid ;Interleukin 6 ;Interleukin 6 gene polymorphisms;

Countries

China

Contacts

Public ContactChen Demin

Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region

chen627@163.com+86 150 7718 6027

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026