Prostate cancer
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.It was confirmed as prostate cancer by histopathology 2. Locally high-risk prostate cancer (Gleason >=8 / PT3-4 or PSA > 20 ng·mL?¹) 3. It can provide complete tumor tissues, surrounding microenvironment tissues and matched blood samples, meeting the requirements of spatial multi-omics technology analysis; 4. The patient can understand and sign the informed consent form, agreeing to participate in the research and sample collection. 5. Adult patients aged 18 and above; 6. The sample quality meets the requirements for subsequent high-throughput spatial omics technology analysis (such as RNA quality and tissue preservation integrity).
Exclusion criteria
Exclusion criteria: 1.Patients with a history of other malignant tumors (unless they have been cured for more than 5 years); 2. Prostate cancer with rare or mixed histological subtypes; 3. Pregnant or lactating women; 4. There are severe cardiovascular, liver or kidney dysfunction, or active infections and other diseases that significantly affect the research results; 5. Simultaneously participate in other clinical trials that may interfere with this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of genes, proteins, and metabolites; | — |
Countries
China
Contacts
Public ContactChen Wei
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed