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The Impact of Abdominal Compression on Breast Motion and Normal Tissue Dose in Radiotherapy After Breast-Conserving Surgery: A Prospective Self-Controlled Study

The Impact of Abdominal Compression on Breast Motion and Normal Tissue Dose in Radiotherapy After Breast-Conserving Surgery: A Prospective Self-Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111880
Enrollment
Unknown
Registered
2025-11-06
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Experimental Group:Abdominal Compression

Sponsors

Department of Radiotherapy, Peking University Shougang Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Female, aged 18 to 70 2. Pathologically confirmed breast cancer, underwent breast-conserving surgery + sentinel lymph node/axillary dissection 3. Total breast radiotherapy +/- tumor bed dose escalation is required 4.ECOG score: 0-1, compatible with pressurization devices 5. Sign the informed consent form

Exclusion criteria

Exclusion criteria: 1. Previous history of thoracic radiotherapy 2. Severe cardiopulmonary diseases (COPD, heart failure NYHA grade III-IV) 3. History of abdominal surgery or abdominal wall hernia 4.BMI >30 kg/m ² (As the thickness of the abdominal wall may affect the pressure transmission effect and consistency of the pressurization device) 5. Mental disorders prevent one from following instructions

Design outcomes

Primary

MeasureTime frame
Dosimetric parameters;The systematic displacement and amplitude of motion of the breast;

Secondary

MeasureTime frame
The incidence rate of radiation pneumonitis;

Countries

China

Contacts

Public ContactYang Yuanyou

Peking University Shougang Hospital

beijingyangyuanyou@163.com+86 136 2121 7196

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026