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The effect of early high-flow nasal oxygen therapy versus conventional oxygen therapy after extubation on hypoxemia during post-interventional bronchoscopy recovery

The effect of early high-flow nasal oxygen therapy versus conventional oxygen therapy after extubation on hypoxemia during post-interventional bronchoscopy recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111870
Enrollment
Unknown
Registered
2025-11-06
Start date
2025-11-06
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative hypoxemia

Interventions

High-flow nasal oxygen therapy group (Group H):Group H was given high-flow nasal cannula oxygen therapy using the Yuyue High-Flow Respiratory Humidification Therapy Device (Model: HF-75A), with the pa
Ordinary nasal catheter oxygen inhalation group (Group C):Group C was given ordinary nasal cannula oxygen inhalation at 2-8L/min.

Sponsors

East Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Aged 18-70 years old, regardless of gender; 2) Patients scheduled for interventional bronchoscopy; 3) American Society of Anesthesiologists (ASA) Class I-III; 4) BMI 18-28kg/m^2;

Exclusion criteria

Exclusion criteria: The subject explicitly refuses to participate in this study; Patients identified as having difficult airway management (Modified Mallampati Score of Grade IV); Patients with preoperative cardiopulmonary insufficiency such as respiratory failure, severe atrioventricular block, severe sinus node dysfunction, and congestive heart failure; Patients with a body mass index (BMI) greater than 35, those requiring emergency surgery, those with a history of previous lung surgery, pneumothorax, pulmonary tuberculosis, or pleural effusion; Patients with a history of abnormal postoperative anesthetic recovery.

Design outcomes

Primary

MeasureTime frame
Incidence rate of hypoxemia during recovery(defined as Spo2 < 90% lasting for more than 10 seconds or Pao2:Fio2 ratio < 300 mm Hg);

Secondary

MeasureTime frame
Number of patients receiving airway rescue(defined as requiring mask non-invasive positive pressure ventilation or reintubation);Arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2);

Countries

China

Contacts

Public ContactHuihong Lu

East Hospital Affiliated to Tongji University

Lucaswj@126.com+86 136 0160 8839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026