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Comparison on Neurological Complications in Labor Analgesia between Spinal-Epidural Anesthesia and Conventional Combined Spinal-Epidural Anesthesia

Comparison on Neurological Complications in Labor Analgesia between Spinal-Epidural Anesthesia and Conventional Combined Spinal-Epidural Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111828
Enrollment
Unknown
Registered
2025-11-06
Start date
2024-02-10
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurological Complications in Labor Analgesia. Common neurological complications include post-dural puncture headache, epidural hematoma, transient neurological symptoms, cauda equina syndrome, nerve root injury, and other neurological complications (permanent nerve injury and infectious complications).

Interventions

Combined Spinal-Epidural Anesthesia Group (Group SA-EA ):Combined Spinal-Epidural Anesthesia
Spinal-Epidural Anesthesia Group (Group SA-EA ):Spinal-Epidural Anesthesia

Sponsors

Shaanxi Provincial People Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Voluntary application by the parturient; 2. After assessment by an obstetrician, the patient is eligible for vaginal delivery or trial of labor.

Exclusion criteria

Exclusion criteria: 1. The parturient refuses to consent and declines to sign the informed consent form. 2. The parturient is unable to cooperate with the performance of neuraxial puncture. 3. Presence of contraindications to neuraxial blockade, such as coagulopathy, infection or trauma at the puncture site, uncorrected maternal hypovolemia or hypotension, increased intracranial pressure, severe spinal deformity, etc. 4. Allergy to local anesthetics or opioids. 5. Presence of neurological diseases or neuropathies that are contraindications to neuraxial analgesia, such as patients with platelet dysfunction and/or coagulopathy, including those receiving anticoagulant therapy (e.g., antiplatelet agents, anticoagulant drugs) or with abnormal platelet function.

Design outcomes

Primary

MeasureTime frame
Occurrence of complications related to nerve blocks;

Secondary

MeasureTime frame
Analgesic quality;Analgesic effect;Maternal outcomes;Fetal outcomes;

Countries

China

Contacts

Public ContactCheng Yan

Shaanxi Provincial People Hospital

anesthesia12138@163.com+86 136 0916 6817

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 25, 2026