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Clinical Study of Thalidomide for Night Sweats in Pancreatic Cancer Patients Receiving Chemotherapy

Clinical Study of Thalidomide for Night Sweats in Pancreatic Cancer Patients Receiving Chemotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111827
Enrollment
Unknown
Registered
2025-11-06
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Night sweats

Interventions

Experimental group:Take 100mg of thalidomide orally every night before bedtime.

Sponsors

Nanjing BenQ Mecical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Pancreatic cancer chemotherapy patients presenting with night sweats; 2.Aged between 18 and 80 years; 3.Individuals who provide informed consent to participate in the study and cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1.Children; 2.Pregnant women or women of childbearing potential not using reliable contraception; 3.Lactating women (or Breastfeeding women); 4.Patients with an absolute neutrophil count (ANC) <=750/mm^3; 5.Patients already using thalidomide analogues or other anti-anhidrotic medications; 6.Patients with a history of seizures or other risk factors for seizure disorders; 7.Patients with tuberculosis, HIV-positive status, or a history of such infections; 8.Patients without fever or symptoms of acute infection and in whom medication review reveals no identifiable cause for night sweats; 9.Individuals who decline to participate in the study.

Design outcomes

Primary

MeasureTime frame
Night Sweats Response Rate;Drug safety;

Secondary

MeasureTime frame
Overall Survival (OS);Improvement in quality of life (QoL);

Countries

China

Contacts

Public ContactJing Zhu

Nanjing BenQ Mecical Center

zhujing_371520337@qq.com+86 25 52238800

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026