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Systematic Diagnosis and Treatment Strategies and Key Technological Innovations of Oncolastic and Reconstructive Surgery in Breast Cancer

Systematic Diagnosis and Treatment Strategies and Key Technological Innovations of Oncolastic and Reconstructive Surgery in Breast Cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111821
Enrollment
Unknown
Registered
2025-11-06
Start date
2024-02-02
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Interventions

Experimental group:Preoperatively, three-dimensional finite element simulation and artificial intelligence technology are used to simulate the three-dimensional morpholo

Sponsors

Plastic Surgery Hospital,Peking Union Medical College Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral breast cancer who are candidates for breast-conserving surgery, mastectomy with prosthetic breast reconstruction, and deep inferior epigastric perforator flap breast reconstruction mainly include: (1) early breast cancer in clinical stage I or II, with tumor size belonging to T1 and T2 stages, and with appropriate breast volume, appropriate tumor-breast volume ratio, and who can maintain a good breast shape after surgery. (2) Sufficient skin and fat tissue in the lower abdomen; (3) No severe sagging of the healthy breast.

Exclusion criteria

Exclusion criteria: Contraindications of breast-conserving and breast reconstructive surgeries mainly include: (1) breast cancer during pregnancy; (2) extensive lesions that make it difficult to achieve negative margins or an ideal breast-conserving appearance; (3) diffusely distributed calcifications with malignant characteristics; (4) tumors with positive margins after extensive local excision, but pathologically negative margins cannot be guaranteed after re-excision; (5) inflammatory breast cancer; (6) other contraindications to breast-conserving and breast reconstructive surgeries.

Design outcomes

Primary

MeasureTime frame
Accuracy of simulation of breast morphology after breast cancer and breast reconstruction based on artificial intelligence and finite element analysis model;

Secondary

MeasureTime frame
Evaluation of a decision support system for patients with breast cancer and breast reconstruction;Breast symmetry assessment;Quality of life rating scale;

Countries

China

Contacts

Public ContactChunjun Liu

Plastic Surgery Hospital,Peking Union Medical College Chinese Academy of Medical Sciences

lancet007@126.com+86 10 8555 7939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026