Mechanical ventilation for critically ill patients
Conditions
Interventions
BIPAP Invasive Mechanical Ventilation Mode:BIPAP Invasive Mechanical Ventilation Mode
P-AC Invasive Mechanical Ventilation Mode:P-AC Invasive Mechanical Ventilation Mode
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 80 years; 2. Expected mechanical ventilation duration >=48 hours; 3. Skin integrity over the diaphragm ultrasound detection area is fully exposed; 4. Patients or their families have provided informed consent to participate in the clinical trial and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with absent spontaneous breathing due to disease; 2. Patients with neuromuscular disorders, such as Guillain-Barré syndrome or myasthenia gravis, causing diaphragmatic dysfunction; 3. Patients with anatomical diaphragmatic abnormalities or unilateral diaphragmatic dysfunction; 4. Patients where diaphragm measurement is impossible via ultrasound, such as those with pneumothorax, excessive body weight, pregnancy, seizures, or abdominal compartment syndrome; 5. Patients with >48 hours of mechanical ventilation within 6 months prior to admission; 6. Patients on fully controlled ventilation mode; 7. Patients judged by clinicians to have poor short-term prognosis, i.e., those receiving palliative care, severely debilitated, with critical hemodynamic instability, requiring end-of-life resuscitation, or highly likely to die within seven days; 8. Patients with primary pulmonary diseases severely impairing lung function, such as tumors, severe ARDS (oxygenation index < 100), active pulmonary tuberculosis, or pleural thickening and adhesions; 9. Patients with secondary diseases severely impairing lung function that cause acute exacerbation of pulmonary symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickening score; | — |
Countries
China
Contacts
Public ContactJing Tang
The First Hospital of Jilin University
Outcome results
None listed