Patients with consciousness disorders
Conditions
Interventions
taVNS group:Using percutaneous transcutaneous auricular vagus nerve stimulation
MNS group:Using median nerve electrical stimulation
taVNS+MNS group:Using percutaneous transcutaneous auricular vagus nerve stimulation combined with median nerve electrical stimulation.
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years; 2. Meets diagnostic criteria for impaired consciousness; 3. Family members willing to participate in the study and sign the relevant informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with unstable vital signs; 2. Those undergoing administration of anesthetic or sedative medications; 3. Individuals with a history of pacemaker or other implantable device placement; 4. Individuals with contraindications to transcutaneous vagus nerve stimulation (taVNS); 5. Individuals with contraindications to median nerve stimulation; 6. Individuals with frequent epileptic seizures; 7. Pregnant women; 8. Individuals with concomitant severe systemic diseases expected to impact assessment outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRS-R score; | — |
Secondary
| Measure | Time frame |
|---|---|
| GCS score;FOUR score;EEG indicators;ERP;fMRI indicators; | — |
Countries
China
Contacts
Public ContactJianxiong Wang
The Affiliated Hospital of Southwest Medical University
Outcome results
None listed