Biological age
Conditions
Interventions
FMD intervention group:The FMD regimen (Caloric intake: Day 1: ~1100 kcal
Days 2-5: ~740 kcal) is administered for 5 days per month.
Control group:Maintain their usual dietary habits and lifestyle.
Sponsors
Wuhan University
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.Aged 30-50 years. 2.Permanent local resident with no plans for long-distance travel within one year. 3.Willing and able to comply with the trial protocol, including completing questionnaires and undergoing procedures such as blood collection.
Exclusion criteria
Exclusion criteria: 1.Diagnosis of severe metabolic diseases or major chronic conditions (e.g., renal failure, malignant tumors). 2.Diagnosed coagulation disorders, severe anemia, or other contraindications for blood draw. 3.Participation in other interventional trials within the past 3 months. 4.Females who are currently pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biological age; | — |
Secondary
| Measure | Time frame |
|---|---|
| General questionnaire survey (including age, gender, education level, income level, and occupation type);Physical examination and physical fitness assessment (including weight, height, heart rate, blood pressure, etc.);Laboratory indicator testing (including metagenomic sequencing, metabolomics, peripheral blood mononuclear cell (PBMC) single-cell analysis, DNA methylation, facial skin characteristics, complete blood count, and biochemical tests); | — |
Countries
China
Contacts
Public ContactRong Shuang
Wuhan University
Outcome results
None listed