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The impact of lactate clearance on the development of post-traumatic stress disorder in severe trauma patients

The impact of lactate clearance on the development of post-traumatic stress disorder in severe trauma patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111800
Enrollment
Unknown
Registered
2025-11-06
Start date
2024-12-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic Stress Disorder

Interventions

post-traumatic stress disorder group:Nil
Non-post-traumatic stress disorder group:Nil

Sponsors

First Aid Center of Affiliated Hospital of Xuzhou Medical University, Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who have experienced trauma within less than 24 hours, have an Injury Severity Score (ISS) greater than 16 points, were first diagnosed in our hospital and admitted to the Intensive Care Unit (ICU); 2. Patients aged 18 years old or above; 3. Patients who, one month after the trauma, have stable emotions, are able to understand and cooperate in answering questions, and can complete the questionnaire effectively; 4. Patients without missing basic data.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of severe liver and kidney diseases, hematological diseases, or malignant tumors and other difficult-to-treat diseases in the past; 2. Patients who are unable to understand, fail to cooperate, or refuse to complete the relevant medical history inquiries and scales; 3. Patients with a history of severe mental disorders or a history of taking psychotropic drugs in the past; 4. Patients with substance abuse such as drug addiction, alcohol dependence, etc. who have received relevant psychological treatment; 5. Patients with severe nerve damage (severe traumatic brain injury, massive intracerebral hemorrhage, large-area cerebral infarction, severe intracranial infection) resulting in complete impairment of cognition.

Design outcomes

Primary

MeasureTime frame
Lactate clearance rate;The PTSD checklist-civilian version;Depression/anxiety self-assessment scale rating;Lactic acid;

Secondary

MeasureTime frame
Injury Severity Score (ISS);Acute Physiology and Chronic Health Evaluation scoring;Serum creatinine;Mean arterial pressure;

Countries

China

Contacts

Public ContactYan Xianliang

First Aid Center of Affiliated Hospital of Xuzhou Medical University, Jiangsu Province

docyxl@163.com+86 189 5215 9710

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026