none
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy women aged 18-74 years old; 2.Having lived in the test area for more than 5 years (not limited to cities);
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women (ascertained by verbal inquiry); 2.Those with scars, pigmentation, atrophy, port-wine stains, or other blemishes, as well as tattoos, on the face, neck, or arms; 3.Those with highly sensitive constitutions, a history of allergic diseases, or skin diseases; 4.Those who have used hormonal drugs or immunosuppressants in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin firmness; | — |
Secondary
| Measure | Time frame |
|---|---|
| skin melanin;stratum corneum moisture content;skin lipids;eye bag volume;pore size;skin texture;measurement of trans-epidermal water loss;skin roughness;erythema area;skin heme;skin surface pH value;ocular wrinkle volume;metagenomic analysis;volume and area of color spots;neck wrinkle volume and area;skin elasticity;ocular wrinkle count;ocular wrinkle area;porphyrin content; | — |
Countries
China
Contacts
Southern Medical University Dermatology Hospital (Guangdong Provincial Dermatology Hospital)