Skip to content

The therapeutic effect of miltiorrhiza polyphenol acid combined with decompressive craniectomy in the treatment of large-area cerebral infarction

The therapeutic effect of miltiorrhiza polyphenol acid combined with decompressive craniectomy in the treatment of large-area cerebral infarction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111768
Enrollment
Unknown
Registered
2025-11-05
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

large-area cerebral infarction

Interventions

The control group :Patients in the control group received decompressive craniectomy treatment.
The observation group:Patients in the observation group received pharmic treatment on the basis of those in the control group.

Sponsors

Tangshan Workers' Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. All patients conformthe diagnostic criteria for extensive cerebral infarction. They are confirmed to have cerebral infarction through CT or magnetic resonance imaging. The infarction lesions shown by CT or head MRI were larger than 4 cm. 2.The surgical indications for all patients were clear. 3. All patients received decompressive craniectomy treatment. 4. All patients had not received thrombolytic therapy within 72 hours prior to enrollment.

Exclusion criteria

Exclusion criteria: 1. Exclude those under the age of 35 and over 70; 2. Exclude patients with hematological diseases, malignant tumors, or liver and kidney dysfunction; 3. Exclude those allergic to the drugs used in the study; 4. Exclude patients with hypertension, heart disease, etc.; 5. Exclude pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
NIHSS scores;

Secondary

MeasureTime frame
infection rate;

Countries

China

Contacts

Public ContactLiQian

Tangshan Workers' Hospital

dansematilian@126.com+86 156 1353 0070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026