Depression
Conditions
Interventions
Venlafaxine treatment group:NA
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with depression through DSM-5, aged 18-65 years old; 2. Baseline HAMD-17 score of 7 or above; 3. First occurrence or recurrence without medication use (> 3 months); 4. No significant risk of suicide (score of the suicide item in the Hamilton Depression Rating Scale is less than 3 points).
Exclusion criteria
Exclusion criteria: 1. Patients with mental disorders such as bipolar disorder and schizophrenia; 2. Patients with refractory depression (those who have failed to respond to >= 2 types of adequate antidepressant treatments in the past); 3. Patients with severe physical illnesses; 4. Substance abusers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17-item scale score;Pharmacogenomics;proteomics;metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Venlafaxine concentration; | — |
Countries
China
Contacts
Public ContactTian Haihua
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed