knee osteoarthritis
Conditions
Interventions
Group A:Radiotherapy dose 0.5Gy/f
Group B:Radiotherapy dose 0.75Gy/f
Group C:Radiotherapy dose 1.0Gy/f
Sponsors
Yueyang Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age range: 40-75 years old; 2. Clarify inflammatory knee arthritis, including clear local inflammation on knee MRI or the possibility of extracting knee joint effusion; Elevated inflammatory indicators such as NE count, ESR, CRP, IL-6, etc. in blood/joint effusion tests; 3. KL score II-III KOA or VAS = 5 points; 4. NSAIDs are ineffective; 5.BMI<35kg/m²; 6. Medical history lasting for more than 3 months; 7. Overall good health condition; 8. Sign the informed consent form, have good compliance, and have family members cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. History of previous joint replacement, previous radiation therapy for affected joints, previous trauma, rheumatic disease, arterial or venous vascular disease, significant lymphedema, pregnancy or lactation, severe mental illness, and tumor history; 2. Researchers determine accompanying diseases that may affect the safety or completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse events(AEs); | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale(VAS);Range of motion scale; | — |
Countries
china
Contacts
Public ContactWeng Jie
Yueyang Central Hospital
Outcome results
None listed