Diabetic bladder dysfunction
Conditions
Interventions
Sponsors
Shenzhen Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Voluntarily signed informed consent. (2) Age >= 18 years. (3) DBD group and Non-DBD group: Meet diagnostic criteria for T2DM with =5 years of disease duration; Possess complete medical records including bladder symptoms and clinical data related to T2DM. (4) Healthy control group (NC group): Healthy individuals undergoing physical examinations at the same medical center, matched for gender and age with the case groups.
Exclusion criteria
Exclusion criteria: For the DBD group and Non-DBD group: (1) Presence of neuropathy caused by non-DM factors (e.g., spinal cord injury, multiple sclerosis, stroke, spina bifida, Parkinson's disease). (2) Presence of prostate disease (e.g., benign prostatic hyperplasia, prostate cancer, history of prostate surgery). (3) Presence of pelvic disease (e.g., pelvic organ prolapse, history of pelvic surgery). (4) Presence of acute metabolic complications of DM (e.g., diabetic ketoacidosis, hyperosmolar hyperglycemic state). (5) Presence of severe cardiac, hepatic, pulmonary, or renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity, specificity, negative predictive value and positive predictive value of plasma exosome-specific proteins for diagnosing DBD;Sensitivity, specificity, negative predictive value and positive predictive value of protein chip diagnostics for DBD (new cohort population); | — |
Countries
China
Contacts
Public ContactCai Wenzhi
Shenzhen Hospital, Southern Medical University
Outcome results
None listed