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Clinical study of transcutaneous auricular vagus nerve stimulation to improve the recovery of hemiplegic limb function after intracerebral hemorrhage by inhibiting inflammatory response

Clinical study of transcutaneous auricular vagus nerve stimulation to improve the recovery of hemiplegic limb function after intracerebral hemorrhage by inhibiting inflammatory response

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111721
Enrollment
Unknown
Registered
2025-11-05
Start date
2024-11-02
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemiplegic patient after cerebral hemorrhage

Interventions

Control group:Percutaneous auricular vagus nerve electrical pseudo-stimulation

Sponsors

The Second Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants who have been informed about the study and have signed the informed consent form; 2. Meet the diagnostic criteria for hemorrhagic stroke as outlined in the "Key Points for the Diagnosis of Various Cerebrovascular Diseases" approved by the 4th National Cerebrovascular Academic Conference of the Chinese Medical Association, with the lesion location and nature confirmed by CT or MRI; 3. Aged 18-60 years; 4. Within 2-4 weeks, with a Glasgow Coma Scale (GCS) score of 14 or above and a Fugl-Meyer Motor Function Assessment score of 20-50; 5. Have not received similar rehabilitation before; 6. Vital signs are stable, condition is not deteriorating, and able to undergo rehabilitation therapy.

Exclusion criteria

Exclusion criteria: 1.People with cognitive or intellectual disabilities; 2.Patients with co-infection, severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction and other neurological diseases; 3.Patients with a local infection or absence of the left ear; 4.Patients with artificial devices such as pacemakers.

Design outcomes

Primary

MeasureTime frame
Fug-Meyer Motor Function Rating Scale score;Activities of Daily Living Scale score;

Secondary

MeasureTime frame
Changes in inflammatory cytokines in peripheral blood;FA and MD values for DTI imaging;

Countries

China

Contacts

Public ContactSun Chao

The Second Affiliated Hospital of Soochow University

sunchao_0512@163.com+86 13913569457

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026