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A retrospective multicentre cohort study on maternal and foetal health outcomes before and after the adjustment of China's COVID-19 control policies

A retrospective multicentre cohort study on maternal and foetal health outcomes before and after the adjustment of China's COVID-19 control policies

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111710
Enrollment
Unknown
Registered
2025-11-04
Start date
2023-12-12
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel coronavirus pneumonia

Interventions

Control group:None
Exposure group:None

Sponsors

Shenzhen Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Time grouping: - Control group: Pregnant women who completed the first trimester (the first 12 weeks of pregnancy) before December 31, 2022. - Exposure Group: Pregnant women who completed the first trimester of pregnancy (the first 12 weeks of pregnancy) on or after January 1, 2023. 2. Gestational age range: - The first trimester is defined as the first 12 weeks of pregnancy. Pregnant women who have a spontaneous abortion in the early stage of pregnancy (before 12 weeks) may also be due to infection People who have had miscarriages due to COVID-19 cannot be ruled out. Whether a pregnant woman was infected with COVID-19 in the early stage of pregnancy or in the middle or late stage of pregnancy, we will not make a distinction for the time being and will include all of them in the study. 3. Data accessibility: - Pregnant women need to undergo mid-pregnancy (20-28 weeks) anatomical screening ultrasound at the participating hospital, or have a complete pregnancy outcome Medical records (first page of the medical record).

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancies: Pregnant women with twin or more pregnancies. 2. Other infections: Concurrent infection with other pathogens that may affect fetal development during pregnancy (such as cytomegalovirus, rubella virus, etc.). 3. Past diseases: The pregnant woman has a history of serious chronic diseases or genetic diseases (such as diabetes, congenital heart disease, etc.). 4. Missing data: Cases lacking key data or with poor data quality.

Design outcomes

Primary

MeasureTime frame
Fetal Development Abnormalities/Anomalies;

Secondary

MeasureTime frame
Pregnancy Outcomes;COVID-19 Infection;

Countries

China

Contacts

Public ContactFu Liang

Shenzhen Third People's Hospital

flk1981@qq.com+86 755 6122 2333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026