Fetal chromosomal disorders Fetal anatomy screening
Conditions
Interventions
Gold Standard:Screening of fetal structure in the first trimester: Nuchal translucency (NT) and structural malformations of the fetus. Serum biomarker: pregnancy-associated plasma protein-A (PAPP-A).
Index test:1. Serum biomarker: pregnancy-associated plasma protein-A (PAPP-A). Free ß-hCG (ß-human Chorionic Gonadotropin)
2. Fetal anatomical screening in the first trimester
3. Fetal structure scree
Sponsors
Hefei Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. No previous history of mental disorders, able to communicate freely; 2. Voluntarily agreed to join the cohort, and pregnant women (or their immediate family members) have signed the informed consent form. 3. Good compliance with follow-up.
Exclusion criteria
Exclusion criteria: 1. Has mental illnesses such as schizophrenia or depression; 2. Clinical data is incomplete or difficult to obtain; 3. Has not obtained informed consent and signed the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactZheng mingming
Hefei Maternal and Child Health Hospital
Outcome results
None listed