Postoperative pain after cesarean section
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for cesarean section of the lower uterine segment under minimally invasive spinal anesthesia; 2. Term 37-41 gestational weeks; 3. Singleton pregnancy; 4. Aged 20-40years; 5. BMI 21.0-35.0 kg/m^2; 6. ASA grade II or III.
Exclusion criteria
Exclusion criteria: 1. Any related major cardiac or respiratory disease, hematological system disease or coagulation parameter disorder, pre-existing vital organ dysfunction (such as liver and kidney failure). 2. Contraindications of neuraxial anesthesia and nerve block. 3. Severe pregnancy complications (high-risk pregnancy such as severe preeclampsia, placental abruption and complete placenta previa). 4. Known fetal abnormalities. 5. History of chronic pain. 6. Patients with mental disorders or inability to understand NRS scores. 7. Patients allergic to opioid or liposomal bupivacaine. 8. Patients who refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The consumption of opioid drugs within 0-72 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Area under the 0-72 hours pain numerical score curve (AUC);NRS score at rest;NRS scores during cough/activity;Patient comfort score (BCS);Mean arterial pressure;Heart rate;Rescue analgesia was required after operation;Time for getting out of bed and moving around;Length of stay;The time of the first postoperative intestinal exhaust;Satisfaction with postoperative analgesia;The incidence of complications; | — |
Countries
China
Contacts
Hefei Maternal and Child Health Hospital