Colon cancer
Conditions
Interventions
Sevoflurane group:Sevoflurane combined with remifentanil TCI was used to maintain anesthesia after tracheal intubation
Rimazolam group:Anesthesia was maintained by Rimazolam combined with remifentanil TCI pump injection after tracheal intubation.
Sponsors
People's Hospital of Jianyang City
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=65 years old; 2. Laparoscopic colorectal cancer surgery under general anesthesia is planned, with an estimated operation time of more than 2 hours. 3.ASA classification: 2 to 3 grades.
Exclusion criteria
Exclusion criteria: 1. Allergic to research drugs such as remimazolam or sevoflurane; 2. There was cognitive dysfunction before the operation; 3. Severe hearing impairment; 4. History of mental illness or long-term use of sedative or antidepressant drugs; 5. There are severe organic diseases, such as liver and kidney dysfunction; 6.BMI >35kg/m^2; 7. The researcher determined that the participant was not suitable for this researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The QOR-15 score 24 hours after the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to complete recovery (MOAA/S reaches 5 points);Incidence of nausea and vomiting within 24 hours after operation;Incidence of delirium during hospitalization after surgery;Length of hospital stay after surgery;Time for BIS value to recover to 80;Time to extubation;Duration of stay in PACU;72 hours after surgery QoR-15 score;Mean arterial pressure and heart rate; | — |
Countries
China
Contacts
Public ContactZhihong Xiong
People's Hospital of Jianyang City
Outcome results
None listed