Clostridioides difficile infection
Conditions
Interventions
Gold Standard:Quantitative Real-time PCR
Index test:Nucleic acid detection based on CRISPR/Cas system
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients aged 18 years or older; 2. Gender: both male and female; 3. Have received antibiotic therapy or chemotherapy within the past 60 days, developed diarrhea after 48 hours of hospitalization, and experienced three or more episodes of diarrhea within 24 hours; 4. Unformed stools (Bristol stool types 5–7).
Exclusion criteria
Exclusion criteria: 1. Patients under 18 years of age; 2. Patients with chronic diarrhea; 3. Those who have used laxatives within 72 hours before screening; 4. Those with a history of unclean food consumption; 5. Other diarrhea with clear causes, such as lactose intolerance; 6. Patients who have already participated in this study and provided a sample once.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Positive Predictive Value;Negative Predictive Value; | — |
Countries
China
Contacts
Public ContactChen Yijian
Institute of Antibiotics, Huashan Hospital, Fudan University
Outcome results
None listed