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Robot navigation compared to CT guidance

A prospective randomized controlled study on the use of puncture robot navigation microwave ablation versus CT-guided microwave ablation in the treatment of lung nodules mainly consisting of ground-glass opacities

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111671
Enrollment
Unknown
Registered
2025-11-04
Start date
2025-11-15
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung nodules primarily with ground-glass opacity

Interventions

Group B control group: CT-guided microwave ablation:CT-guided biopsy
Group A Experimental Group: Microwave Ablation under Puncture Robot Navigation:Puncture Robot Navigation

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 85 years; 2. Chest contrast-enhanced thin-slice high-resolution CT scan: nodules with a size of 3mm to 30mm; 3. Ground-glass opacity component >=75%; 4. Preoperative clinical evaluation shows no hilar or mediastinal lymph node metastasis and no distant metastasis; 5. According to the 8th edition UICC TNM staging system, primary peripheral lung cancer is stage IA, and patients are unable to undergo surgical resection due to poor cardiopulmonary function or advanced age; 6. Patients who refuse or are unwilling to undergo surgical resection; 7. Patients with newly developed or residual small lung nodules after early-stage primary lung cancer surgery (tumor maximum diameter <=3cm, no other metastasis); 8. Patients with a single lung who cannot undergo single-lung surgical resection for various reasons (maximum tumor diameter <=3cm, no other metastasis); 9. Patients with multiple primary lung cancers (maximum tumor diameter <=3cm, unsuitable for surgical resection, no other metastatic lesions). ? Preoperative ECOG performance status score 0/1; 10. ASA score I-III; 11.Voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Smoking cessation time < 2 weeks; 2. Lesion located near the main trunk of the pulmonary artery and vein; 3. Lesion adjacent to the hilum, located next to the lobar bronchus; 4. Pregnant or lactating women; 5. Patients with severe mental illness; 6. History of other malignancies within 5 years; 7. History of unstable angina or myocardial infarction within 6 months, coronary angiography shows severe stenosis of major coronary branches; 8. History of cerebral infarction or cerebral hemorrhage within 6 months; 9. Continuous systemic corticosteroid treatment within 1 month; 10. Patients deemed unsuitable for trial participation by the investigator; 11. Patients or their authorized representatives unwilling to sign written informed consent or unwilling to comply with the study protocol; 12. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Puncture Accuracy;

Countries

China

Contacts

Public ContactZhang Shuliang

Fujian Medical University Union Hospital

670627941@qq.com+86 591 83357896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026