Lung nodules primarily with ground-glass opacity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 85 years; 2. Chest contrast-enhanced thin-slice high-resolution CT scan: nodules with a size of 3mm to 30mm; 3. Ground-glass opacity component >=75%; 4. Preoperative clinical evaluation shows no hilar or mediastinal lymph node metastasis and no distant metastasis; 5. According to the 8th edition UICC TNM staging system, primary peripheral lung cancer is stage IA, and patients are unable to undergo surgical resection due to poor cardiopulmonary function or advanced age; 6. Patients who refuse or are unwilling to undergo surgical resection; 7. Patients with newly developed or residual small lung nodules after early-stage primary lung cancer surgery (tumor maximum diameter <=3cm, no other metastasis); 8. Patients with a single lung who cannot undergo single-lung surgical resection for various reasons (maximum tumor diameter <=3cm, no other metastasis); 9. Patients with multiple primary lung cancers (maximum tumor diameter <=3cm, unsuitable for surgical resection, no other metastatic lesions). ? Preoperative ECOG performance status score 0/1; 10. ASA score I-III; 11.Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Smoking cessation time < 2 weeks; 2. Lesion located near the main trunk of the pulmonary artery and vein; 3. Lesion adjacent to the hilum, located next to the lobar bronchus; 4. Pregnant or lactating women; 5. Patients with severe mental illness; 6. History of other malignancies within 5 years; 7. History of unstable angina or myocardial infarction within 6 months, coronary angiography shows severe stenosis of major coronary branches; 8. History of cerebral infarction or cerebral hemorrhage within 6 months; 9. Continuous systemic corticosteroid treatment within 1 month; 10. Patients deemed unsuitable for trial participation by the investigator; 11. Patients or their authorized representatives unwilling to sign written informed consent or unwilling to comply with the study protocol; 12. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Puncture Accuracy; | — |
Countries
China
Contacts
Fujian Medical University Union Hospital