diaphragmatic dysfunction
Conditions
Interventions
Group A(0.5% Hydrochloride Bupivacaine 20ml):None
Group B(0.5% Hydrochloride Bupivacaine 10ml + Liposomal Bupivacaine 10ml):None
Sponsors
The First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing upper limb surgery scheduled for interscalene brachial plexus block; 2.Aged >= 18 years; 3.American Society of Anesthesiologists (ASA) physical status I-II; 4. Secure written informed consent from the patient or family members.
Exclusion criteria
Exclusion criteria: 1. Known allergy or intolerance to amide local anesthetics; 2. Nerve injury in the upper limb on the surgical side; 3. Coagulopathy; 4. Used opioid medications continuously for more than 3 weeks before surgery; 5. History of pulmonary disease and a pulse oxygen saturation (SpO2) < 95% (measured after 5 minutes of rest at room temperature without oxygen supplementation, using a transcutaneous pulse oximeter); 6. Refuse to participate or are deemed unsuitable for this trial by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amplitude and phrenic nerve conduction time of diaphragmatic compound muscle action potential; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;Numerical Rating Scale for Pain Intensity; | — |
Countries
China
Contacts
Public ContactDiansan Su;Xiuxia Bao
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed