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Study on the Effect and Satisfaction of Linaloprilide Combined with Compound Polyethylene Glycol Electrolyte Powder on the Intestinal Cleanliness of High-Risk Populations with Insufficient Intestinal Preparation

Study on the Effect and Satisfaction of Linaloprilide Combined with Compound Polyethylene Glycol Electrolyte Powder on the Intestinal Cleanliness of High-Risk Populations with Insufficient Intestinal Preparation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111663
Enrollment
Unknown
Registered
2025-11-04
Start date
2023-08-01
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High-risk groups with inadequate intestinal preparation

Interventions

control group:Compound polyethylene glycol electrolyte 1L for oral administration (at 21:00 the night before colonoscopy) + Compound polyethylene glycol electrolyte 2L for oral administration (6 hours
experimental group:Linalopril 290ug × 1 tablet taken orally (in the early morning of the day before colonoscopy) + Compound Polyethylene Glycol Electrolyte 1L taken orally (at 21:00 on the evening bef
Linalopril 290ug × 1 tablet combined with Compound Polyethylene Glycol Electrolyte Powder 2L taken orally (6 hours before colonoscopy)

Sponsors

Hangzhou Normal University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. At least one of the following conditions must be met in the high-risk group with inadequate intestinal preparation: chronic constipation, body mass index > 25 kg/m^2, age > 70 years, history of colon surgery, accompanied by other diseases (such as diabetes, Parkinson's disease), use of tricyclic antidepressants or anesthetics; 2. Age >= 19 years, gender not restricted; 3. Able to understand the procedures and methods of this study, willing to sign the informed consent form and strictly follow the clinical research protocol to complete this study.

Exclusion criteria

Exclusion criteria: 1. Has a history of acute myocardial infarction or cerebrovascular accident (within 6 months), and has underlying diseases such as severe heart, lung, liver, and kidney dysfunction; 2. Is currently taking anticoagulant drugs such as aspirin and warfarin, or has coagulation dysfunction; 3. Has undergone gastrointestinal resection, accompanied by severe gastroparesis or intestinal obstruction; 4. Has known or suspected gastrointestinal obstruction or perforation; 5. Pregnant or lactating women; 6. Has mental disorders and cannot cooperate with the examination; 7. Is allergic to intestinal preparation drugs; 8. Patients judged by the investigator to be unsuitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Boston bowel preparation scale;

Secondary

MeasureTime frame
Patient satisfaction score;Entry and exit time and rate of colonic intubation;

Countries

China

Contacts

Public ContactWu Jiaqi

Hangzhou Normal University Affiliated Hospital

wujiaqi_12@126.com+86 137 3225 4640

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026