Irritable bowel syndrome
Conditions
Interventions
Experimental Group 1:Main Acupuncture Points: Zusanli, Shangjiuxu
Electroacupuncture: continuous wave (2HZ), current 0-40mA (can be accurate to 0.1mA) range of independent adjustment, as tolerated by
Experimental Group 2:Main Acupuncture Points: Zusanli, Shangjiuxu
Electroacupuncture: continuous wave (100HZ), current 0-40mA (can be accurate to 0.1mA) range of independent adjustment, as tolerated b
Sham Acupuncture Control Group:Acupuncture points: 3 non-meridian and non-acupuncture points were selected, and all needling points were not at meridians and acupoints.
Operation: Disposable sterile f
Healthy Control Group:Only one MRI scan was received during the trial and no treatment was required.
Sponsors
Shaanxi Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 75 years old (inclusive), gender not limited; 2. Meet the diagnostic criteria for subtypes of Rome IV diarrhea-predominant irritable bowel syndrome; 3. In the past two weeks, the daily defecation diary report shows at least 4 days of Bristol stool type 6 or 7 and less than 4 days of Bristol stool type 1 or 2. The average daily abdominal pain score in the past week was >=3 points. 4. No acupuncture treatment has been received in the past six months; 5. No antidepressants or drugs that treat the symptoms of irritable bowel syndrome have been taken within two weeks before treatment, including traditional Chinese medicine or Chinese patent medicine, antidiarrheal drugs, antispasmodics, intestinal antibiotics, probiotic preparations, etc. Only those who meet all the above requirements can be included.
Exclusion criteria
Exclusion criteria: 1.Constipation-type IBS/ mixed IBS, inflammatory bowel disease/microscopic colitis/history of celiac disease/Crohn's disease and other organic bowel diseases. 2. Diabetes, thyroid dysfunction; 3. Severe acute or chronic organic diseases and kidney or liver diseases; 4. Previous history of abdominal surgery (patients who have undergone appendectomy, hemorrhoid surgery, or polyp surgery within more than 3 months can be included); 5. During pregnancy or lactation; 6. History of alcohol and drug abuse; 7. Patients participating in other clinical trials, etc. 8. Contraindications for magnetic resonance imaging: Patients with pacemakers, nerve stimulators, artificial metal heart valves, etc. Those with aneurysm clips (except for non-paramagnetic ones such as titanium alloys); Those with metal foreign bodies in the eye, inner ear implants, metal prostheses, metal prosthetic limbs, metal joints, and ferromagnetic foreign bodies in the body; Patients with severe high fever. Those who meet one or more of the above requirements will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IBS Symptom Severity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effective Response Rate;Irritable Bowel Syndrome Overall Symptoms;Patient Depression Score;Irritable Bowel Syndrome Quality of Life Status;Bowel Movement Frequency;Abdominal Pain Symptoms;Adequate remission of IBS symptoms;Abdominal Bloating Symptoms; | — |
Countries
China
Contacts
Public ContactYang Gaiqin
Shaanxi Provincial Hospital of Chinese Medicine
Outcome results
None listed