Severe Hospital-Acquired Pneumonia
Conditions
Interventions
Study Group (Sputum culture q8h):Sputum culture should be sent for testing every 8 hours.
Control Group (one sputum culture):Single sputum culture
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years and <80 years. 2.Meeting the diagnostic criteria for severe hospital-acquired pneumonia (HAP). 3.Patients who have undergone invasive mechanical ventilation. 4.Informed consent obtained by a legal representative.
Exclusion criteria
Exclusion criteria: 1.Exclusion of mechanically ventilated patients with non-hospital-acquired pulmonary infections. 2.Intensive Care Unit (ICU) length of stay less than 2 days. 3.Cases without authorization or failing to meet ethical review standards for research. 4.For patients with multiple hospitalizations during the study period, only data from the first ICU admission were included for analysis, with subsequent admissions excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-d mortality rate;In-hospital mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of Antibiotic Changes;Bacterial Load Variation;Sputum Quality Classification;Duration of Mechanical Ventilation;Length of ICU Stay;Length of in-hospital Stay;In-hospital costs;Antibiotic Therapy Costs; | — |
Countries
China
Contacts
Public ContactLu Zhonghua
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed