Critical Illness
Conditions
Interventions
Critically ill patients with a hyperinflammatory state:None
Critically ill patients with a hypoinflammatory state:None
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient inclusion criteria were: 1) admission to the ICU with a diagnosis meeting each database's definition of critical illness; 2) receipt of continuous nutritional support for =72 hours during hospitalization to ensure sufficient data for analysis; and 3) availability of lactate dehydrogenase (LDH) laboratory results in the database to facilitate the assessment of inflammatory status.
Exclusion criteria
Exclusion criteria: Exclusion criteria comprised: 1) patients with severe pre-admission malnutrition or long-term specialized nutrition therapy, which could confound the relationship between in-hospital nutritional support and outcomes; 2) patients with comorbidities that significantly alter nutrient metabolism or inflammatory pathways (e.g., rare genetic metabolic diseases, chronic rheumatological inflammatory diseases), as their inclusion would prevent the results from reflecting generalizable patterns; and 3) patients with extensive missing data, specifically on key inflammatory markers, nutritional records, or outcomes, rendering them unsuitable for statistical analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Mechanical Ventilation; Hospital Acquired Infection ; | — |
Countries
The United States
Contacts
Public ContactHongxiang Li
The First Hospital of Jilin University
Outcome results
None listed