Skip to content

A study on the precise localization of individualized transcranial magnetic stimulation based on resting-state functional magnetic resonance imaging in the treatment of depression in children and adolescents

A study on the precise localization of individualized transcranial magnetic stimulation based on resting-state functional magnetic resonance imaging in the treatment of depression in children and adolescents

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111639
Enrollment
Unknown
Registered
2025-11-04
Start date
2023-10-08
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent depressive disorder

Interventions

Classical target group:Precise transcranial magnetic stimulation of classical target positions on the basis of drugs
the left DLPFC-sgACC function connects the targeting group :On the basis of drug therapy, precise transcranial magnetic stimulation was performed for the localization of the functional connection of t

Sponsors

Nanjing Brain Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Those who meet the diagnostic criteria for depressive disorders as stipulated in the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5); 2. Those who meet the diagnostic criteria for major depressive episodes of the International Neuropsychiatric Mini-Questionnaire for Children (MINI-KID); 3. Gender is not limited. Age range: 12 to 18 years old. 4. No physical treatments such as non-convulsive electroconvulsive therapy, transcranial magnetic stimulation therapy, or transcranial direct current stimulation therapy were received within half a year before enrollment. 5. Subjects who can understand and are willing to strictly abide by the clinical trial protocol to complete this trial, and both the subjects and their guardians have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those who have a history or are currently suffering from neuropsychiatric disorders other than depressive disorders; 2. Those who have a history of or are currently suffering from organic brain diseases or chronic severe physical diseases; 3. Those with a history of skull defects, head injuries, or the presence of metal elements or implantable devices in the body; 4. Take immunomodulators and hormone preparations for at least half a year, and take antipyretic and analgesic drugs within two weeks. 5. Those that the researchers consider unsuitable for inclusion.

Design outcomes

Secondary

MeasureTime frame
Hamilton Anxiety Scale score;Self-rating Depression Scale score;Self-rating Anxiety Scale score;Integrated Visual And Auditory Continuous Performance Test, IVA-CPT;

Primary

MeasureTime frame
Hamilton Depression Scale score;

Countries

China

Contacts

Public ContactXiaoyan Ke

Nanjing Brain Hospital

kexynj@hotmail.com+86 133 0517 6562

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026