Sedation
Conditions
Interventions
CS Group (Sober and Calm):Intravenous injection of rifentanyl 0.5 µg/kg, intravenous injection of rimazolam 0.05 ~ 0.1 mg/kg after 1 min
DS Group (Deep Sedation):The anaesthetist administered remifentanil intravenously at 0.5 µg/kg. One minute later, remimazolam was administered intravenously at 0.1–0.2 mg/kg, with an infusion rate of
Sponsors
Zigong Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
24 Years to 68 Years
Inclusion criteria
Inclusion criteria: A total of 140 obese patients undergoing diagnostic gastroscopy were selected, with all subjects meeting the following inclusion criteria: 1. Aged 24–68 years with American Society of Anesthesiologists (ASA) physical status score II; 2. Estimated gastroscopy procedure duration within 20 minutes; body mass index (BMI) 30–35 kg/m².
Exclusion criteria
Exclusion criteria: Patients with severe cardiovascular, neuropsychiatric or cerebrovascular diseases who are judged to be difficult to control the respiratory tract (improved Mallampati grade IV) or obstructive sleep apnea hypoventilation syndrome (OSAHS) are excluded. In addition, pregnant or lactating women, patients who are allergic to propofol, benzodiazepines or opioids, and patients who have sedation or surgical contraincontraindications that researchers believe affect their safety are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of SpO2 values < 95% and < 90% in patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of successful sedation;Patient and endoscopist satisfaction scores; | — |
Countries
China
Contacts
Public ContactLiJun
Zigong Fourth People's Hospital
Outcome results
None listed