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Efficacy Evaluation of RF-CBT in Improving Emotional Dysregulation in Adult ADHD: A fMRI-based Single-Arm Trial

Efficacy Evaluation of RF-CBT in Improving Emotional Dysregulation in Adult ADHD: A fMRI-based Single-Arm Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111621
Enrollment
Unknown
Registered
2025-11-03
Start date
2025-11-03
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficit hyperactivity disorder

Interventions

Experimental Group:Rumination-Focused Cognitive Behavioral Therapy

Sponsors

Chongqing Mental Health Center,
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.The adult ADHD diagnosis interview (DIVA-5) met the adult ADHD diagnostic criteria in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). 2. The score of the Short version of the Emotional Regulation Difficulty Questionnaire (DERS-16) is >=48 points. 3. Aged 18 to 45, gender not limited. 4. The IQ was assessed as > 90 by the Wechsler Intelligence Scale (WASI). 5. Currently, there are dosage-stable ADHD treatment drugs and anti-anxiety and anti-depression drugs available, but the dosage has not been adjusted in the past 4 weeks and the drugs have not been changed in the past 6 weeks. 6. Have not taken any ADHD treatment drugs or anti-anxiety and anti-depression medications, or have stopped taking them for more than one month.

Exclusion criteria

Exclusion criteria: 1. There is a planned or intended suicidal tendency in the current or past six months as indicated by the Colombian Suicide Severity Questionnaire (C-SSRS). 2. Other mental illness states that cannot understand and cooperate to complete the research, such as autism spectrum disorder, obsessive-compulsive disorder, major depressive episode, bipolar disorder manic/major depressive episode, schizophrenia, schizoaffective disorder, paranoid mental disorder, substance abuse, etc. (mild to moderate anxiety and depressive disorders are not excluded). 3. Currently, in addition to anti-anxiety, anti-depression and ADHD treatment drugs, other psychotropic medications are being used, such as mood stabilizers and antipsychotic drugs. 4. Currently, there are serious physical diseases causing mental symptoms, and in the past, there are neurological diseases such as stroke, cerebral hemorrhage, and head trauma causing loss of consciousness. 5. Previously received systematic CBT and its variants of intervention (such as mindfulness-based cognitive therapy, dialectical behavioral therapy, etc.). 6. Wearing metal braces or retainers, having metal implants in the body, or having tattoos containing metal components. 7. People with claustrophobia. 8. Women who are currently pregnant or preparing for pregnancy.

Design outcomes

Primary

MeasureTime frame
Difficulties in Emotion Regulation Scale-16;

Secondary

MeasureTime frame
Nolen-Hoeksema Ruminative Responses Scale;Heidelberg Form for Emotion Regulation Strategies;Generalized Anxiety Disorder 7-item scale;Patient Health Questionnaire-9;Dynamic Functional Connectivity Strength Under Task-state fMRI;Brain Functional Connectivity Strength Under resting-state fMRI;Activation of ROIs Under Rumination-Induction Tasks;Structure MRI;

Countries

China

Contacts

Public ContactYuchen Zhang

Chongqing Mental Health Center

zzzzycccc@126.com+86 158 2350 2873

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026