Prostate cancer
Conditions
Interventions
Group A:Robot-Assisted Laparoscopic Traditional Anterior Approach Nerve-Sparing Radical Prostatectomy
Group B:robot-assisted laparoscopic posterior approach retzius-sparing nerve-sparing radical prostatectomy
Group C:robot-assisted laparoscopic anterior approach retzius-sparing nerve-sparing radical prostatectomy
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
Male
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pathologically confirmed localized prostate cancer (cT1-2N0M0); 2. Age <= 80 years; 3. Intermediate to low-risk patients based on D'Amico risk stratification: PSA 4-20 ng/ml, Gleason score <= 7, T2b or lower; 4. Patient agrees to randomization and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Preoperative urinary incontinence or neurogenic bladder; 2. History of pelvic or urethral radiotherapy, chemotherapy, surgery, or endocrine therapy; 3. Imaging suggesting suspected lymph node or bone metastasis; 4. Severe cardiopulmonary diseases that cannot tolerate surgery; 5. Presence of metal implants or any condition preventing tolerance of MRI; 6. Patients whom the investigator deems unsuitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| immediate urinary control recovery rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| long-term urinary control recovery rate;pelvic functional MRI-related parameters;progression-free survival;surgical margin; | — |
Countries
China
Contacts
Public ContactBaojun Wang
Department of Urology, Medical Division, Third Medical Center, PLA General Hospital
Outcome results
None listed