Moyamoya disease
Conditions
Interventions
non-occurrence group:no
Occurrence group :no
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with moyamoya disease who underwent vascular bypass surgery at the Hongqiao Campus of Huashan Hospital Affiliated to Fudan University from January 2019 to December 2023; 2.Age: >18 years old, no age limit; Meet the diagnostic criteria of MMD, namely (1)Cerebral angiography or MRA shows stenosis or occlusion of the terminal segments of bilateral middle cerebral arteries and internal carotid arteries, and a large number of abnormal reticular blood vessels are formed around them;(2) Exclude cerebral vascular stenosis or occlusion caused by other reasons, such as atherosclerosis, autoimmune diseases, intracranial infection, etc.; 3.Underwent vascular bypass surgery, including direct bypass and indirect bypass; 4.Completed cranial MRI and MRA examinations before and after surgery, and the imaging data were complete; 5. Complete clinical data and follow-up records, with a follow-up time of >=3 months.
Exclusion criteria
Exclusion criteria: 1. Patients with other serious systemic diseases, such as malignant tumors, severe cardiopulmonary insufficiency, etc.; 2.Patients with severe neurological deficits before surgery, such as hemiplegia, aphasia, etc.; 3. Patients with serious complications during surgery, such as massive hemorrhage, brain herniation, etc.; 4. Patients with non-ischemic complications after surgery, such as intracranial infection, epilepsy, etc.; 5. Patients with incomplete clinical or imaging data; 6.Patients who were lost to follow-up or whose follow-up time was less than 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRs score;MRI/CT/cerebral angiography;Anesthesia type, ART, CVP, BIS, NIRS, target blood pressure range, whether to use phenylephrine/norepinephrine, intraoperative fluid balance (crystalloid, colloid, input-output), intraoperative blood loss, intraoperative blood transfusion (red blood cell suspension, plasma, platelets), preoperative and postoperative oxygenation index (OI = PaO2/FiO2, PaO2: arterial oxygen partial pressure, FiO2: inspired oxygen concentration), intraoperative FiO2, body temperature, whether hypotension occurred d; | — |
Countries
China
Contacts
Public ContactWang Yingwei;Cha Chaochao
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed