Secondary hyperparathyroidism
Conditions
Interventions
Gold Standard:Refer to the diagnostic criteria of the "Chinese Expert Consensus on Clinical Practice of Surgery for Hyperparathyroidism Secondary to Chronic Kidney Disease (2021 Edition)"
Index test:Gender, duration of dialysis, perioperative serum calcium,serum phosphorus, PTH, markers of bone metabolism
Sponsors
The 960th Hospital of the PLA Joint Logistics Support Force
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) At least two regular dialysis sessions per week, with a duration of more than 3 months; (2) Indications for parathyroidectomy (PTX) in renal-related secondary hyperparathyroidism (SHPT): patients with severe secondary hyperparathyroidism, whose serum intact parathyroid hormone (iPTH) level remains above 800 pg/mL and is unresponsive to drug treatment; patients with severe clinical symptoms such as intractable pruritus, fatigue, bone pain, ectopic calcification, erythropoietin-resistant anemia, and dilated cardiomyopathy; patients with severe osteoporosis and skeletal deformities detected through preoperative imaging; (3) Preoperative ultrasound showing multiple parathyroid glands with a diameter =1 cm and rich blood flow; (4) Successful surgery
Exclusion criteria
Exclusion criteria: (1) Presence of other severe diseases or complications; (2) Poor treatment compliance; (3) Patients with poor ultrasound image quality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| calcium;Accuracy;Sensitivity;Specificity;Positive predicative value;negative predictive value; | — |
Countries
China
Contacts
Public ContactQingqing He
The 960th Hospital of the PLA Joint Logistics Support Force
Outcome results
None listed