Myoclonus
Conditions
Interventions
Group A: Etomidate group (0.3 mg/kg):etomidate
Group B: Propofol 0.6 mg/kg + Etomidate group (0.3 mg/kg):propofol
Group C: Propofol 0.8 mg/kg + Etomidate group (0.3 mg/kg):propofol
Group D: Propofol 1.0 mg/kg + Etomidate group (0.3 mg/kg):propofol
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
5 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1.Age 5 ~10 years old; 2.American College of Anesthesiologists (ASA) Grade I- Grade II; 3.Children undergoing elective operation under general anesthesia under tracheal intubation; 4.The guardian of the child signs the informed consent;
Exclusion criteria
Exclusion criteria: 1.10 years old; 2.ASA classification level; 3.The child had a history of allergy to the experimental drug; 4.Serious systemic diseases, such as poorly controlled hypertension, epilepsy, bradycardia, heart block, heart failure, liver failure, mental illness, sepsis or systemic infection, neurological disease, asthma, chronic cough, upper respiratory infection, etc. 5.Recent use of analgesic sedative drugs drug abuse or history of chronic pain; 6.History of adrenocortical insufficiency; 7.The children and their guardians declined to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency and grading of myoclonus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and grading of injection pain;spo2;NBP;HR; | — |
Countries
China
Contacts
Public Contactchi wu
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed