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A Clinical Study of Postoperative Tricuspid Regurgitation Following Aortic Root Surgery

A Clinical Study of Postoperative Tricuspid Regurgitation Following Aortic Root Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111591
Enrollment
Unknown
Registered
2025-11-03
Start date
2025-11-15
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Tricuspid Regurgitation Following Aortic Root Surgery

Interventions

Observational group (Part II):None

Sponsors

Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/ Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Retrospective cohort 1. Patients aged 18–80 years. 2. Had undergone Bentall, David, or Wheat aortic-root surgery at our centre for aortic-root pathology (aortic-valve disease, aortic-root aneurysm, aortic dissection involving the root) without concomitant tricuspid-valve repair or replacement. 3. Intra-operative trans-oesophageal echocardiography performed before cardiopulmonary bypass and after weaning. Prospective cohort 1. Age 18–80 years. 2. Scheduled for Bentall, David, or Wheat aortic-root surgery at our centre for the above-listed aortic-root diseases, with no planned concomitant tricuspid-valve repair. 3. Trans-oesophageal echocardiography planned before bypass and after weaning. 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: Retrospective cohort 1. Missing, unreadable, or uninterpretable intra-operative trans-oesophageal echocardiography images that preclude assessment of tricuspid regurgitation. 2. Loss of key peri-operative data (e.g., length of hospital stay, ICU duration). Prospective cohort 1. Concomitant congenital heart disease or pre-operative moderate-to-severe tricuspid regurgitation. 2. Contra-indications to trans-oesophageal echocardiography: severe oesophageal/gastric ulcer, active upper-GI bleeding, previous oesophageal surgery, oesophageal stricture/obstruction, or congenital oesophageal anomaly. 3. Refusal to provide informed consent.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative increase in tricuspid regurgitation;

Secondary

MeasureTime frame
Rate of reoperation on the tricuspid valve after surgery;Postoperative heart-failure incidence;Heart-failure-related readmission rate after surgery;Postoperative survival time;Postoperative stroke incidence;

Countries

China

Contacts

Public ContactLiu Guangyu

Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/ Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences

liuguangyu@fuwaihospital.org+86 151 1793 9504

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026