Cardiovascular Disease
Conditions
Interventions
Oobservational group:None
Sponsors
Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Participants are Chinese citizens aged >= 18 years old; 2.Participants have clinical manifestations of chest pain and are willing to undergo examinations including coronary angiography, QCA (Quantitative Coronary Angiography), and high-frequency QRS detection; 3.Participants (or their legal guardians) are fully informed and have signed the informed consent form; 4.Participants are willing to complete the follow-up.
Exclusion criteria
Exclusion criteria: 1.General Exclusion Criteria: Participants will be excluded from enrollment if they meet any of the following criteria. (1)With malignant tumor or other diseases where the expected life expectancy is <= 1 year; (2)With moderate or severe depression or other mental illnesses; (3)History of stroke, epilepsy, or severe cognitive impairment that prevents accurate description of one’s own conditions; (4)Participants deemed by investigators unable to complete the study or unsuitable for participating in the trial. 2. Exclusion Criteria for Resting High-Frequency QRS Electrocardiogram Situations where high-frequency QRS signals cannot be collected, including but not limited to patients’ unwillingness or inability to cooperate, poor electrode contact, or inadequate signal transmission. 3. Exclusion Criteria for Exercise Stress High-Frequency QRS Electrocardiogram: Participants will be excluded from undergoing exercise stress high-frequency QRS electrocardiogram if they meet any of the following criteria, but may still be considered for resting high-frequency QRS electrocardiogram collection. (1)Acute ST-segment elevation myocardial infarction (STEMI), or non-ST-segment elevation acute coronary syndrome (NSTE-ACS) assessed as high-risk or higher; (2)Other high-risk chest pain conditions, including recurrent or progressive angina pectoris, dyspnea caused by heart failure, hemodynamic instability, gradually elevated cardiac markers, or malignant arrhythmia; (3)Situations that prevent tolerance of or interfere with the treadmill stress test for high-frequency QRS electrocardiogram, including but not limited to bradyarrhythmia, tachyarrhythmia, or motor system abnormalities; (4)Ejection fraction (EF) <= 40%, or diagnosis of acute heart failure or acute exacerbation of chronic heart failure; (5)With moderate or severe valvular heart disease, or any type of cardiomyopathy; (6)Users of cardiac pacemakers or implantable cardioverter-defibrillators (ICDs); (7)Pericardial diseases and any type of myocarditis; (8)Other situations where investigators consider exercise stress high-frequency QRS electrocardiogram to be inappropriate or unfeasible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coronary Angiography Results;Quantitative Flow Ratio Results;All-Cause Mortality;Recurrent myocardial infarction;Unplanned readmission for heart failure;Left ventricular ejection fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac death;Unplanned readmission for cardiovascular disease;Unplanned Cardiovascular Surgery; | — |
Countries
China
Contacts
Public ContactPan Hongwei
Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)
Outcome results
None listed