Postoperative sleep disorders are manifested as reduced nighttime sleep duration, disordered sleep structure, abnormal circadian rhythm, etc.
Conditions
Interventions
Sponsors
People's Hospital of Jianyang City
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.Plan to undergo laparoscopic colorectal cancer surgery under general anesthesia; 3.ASA classification grade 2 - 3.
Exclusion criteria
Exclusion criteria: 1.The patient refused to sign the informed consent form; 2.The patient has had severe sleep disorders in the past month and needs to receive medical intervention (such as hypnotic drugs). 3.Allergy to study drugs such as remimazolam or sevoflurane; 4.Preoperative cognitive impairment or severe hearing impairment leads to inability to communicate; 5.History of neurological or psychiatric diseases, or long-term use of sedative or anti-anxiety drugs; 6.Severe renal insufficiency (requiring renal replacement therapy); 7.Liver function impairment (Child-Pugh class C); 8.Body Mass Index (BMI) > 35 kg/m^2; 9.Have sleep apnea syndrome or moderate to severe snoring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of sleep disturbances 1 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality score 30 days after surgery;The incidence of sleep disturbances 30 days after surgery;The Pittsburgh Sleep Quality Index (PSQI) score on the 1st day after surgery;Anxiety scores on the 1st, 2nd, and 3rd day after surgery;The incidence of resedation after extubation in PACU;Length of hospital stay after surgery;Pittsburgh Sleep Quality Index (PSQI) score 3 days after surgery;PACU length of stay;The number of times the analgesic pump is pressed and the proportion of rescue analgesia on the 1st, 2nd, and 3rd days after surgery;The incidence of intraoperative awareness;Time of postoperative extubation;The incidence of nausea and vomiting within 24 hours after surgery;The incidence of delirium during postoperative hospitalization;The incidence of bradycardia (HR < 50 beats per minute) 1 day after surgery;Sleep bracelet monitoring indicators on the 1st, 2nd, and 3rd day after surgery;The incidence of sleep disturbances 3 days after surgery;The resting VAS pain scores on the 1st, 2nd, and 3rd day after surgery;The incidence of postoperative hypoxemia (SpO2 < 92%) on the 1st day; | — |
Countries
China
Contacts
Public ContactWenjie Mao
People's Hospital of Jianyang City
Outcome results
None listed