Lschemic stroke
Conditions
Interventions
Gold Standard:Confirmed by cranial MRI/MRA as infarction in the middle cerebral artery territory
Index test:VR Exercise - Cognitive Function Data?Head MRI Diffusion Tensor Imaging
Sponsors
Zhejiang Provincial Tongde Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with subacute ischemic stroke (meeting the diagnostic criteria of the 2025 version of the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke", confirmed by cranial MRI/MRA to have infarction in the middle cerebral artery blood supply area, and the lesion involves the brain regions related to upper limb movement); 2. 7 to 30 days after the onset of the disease, it is within the intervention window period of the subacute stage. 3. Baseline NIHSS score: 3-20 points, FMA-UE score: 32-57 points (with assessable unilateral upper limb motor dysfunction and capable of cooperating with VR motion-cognitive tasks); 4. Clear consciousness (GCS score >=15 points), able to understand and cooperate to complete a 20-minute VR task (MMSE score >=20 points, excluding the interference of cognitive impairment on task execution); 5. No serious musculoskeletal diseases (such as periarthritis of the shoulder, fractures) or history of VR dizziness (no discomfort such as nausea or blurred vision was found in the pre-test); 6. At the 30-day follow-up, the reexamination of FMA-UE (recovery of motor function) and mRS Score (overall functional prognosis) can be completed. 7. Patients and their families who agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Hemorrhagic stroke, transient ischemic attack (TIA), or other neurological disorders (such as multiple sclerosis); 2. Unable to cooperate with DTI examination; 3. The quality of DTI data does not meet the standards (such as motion artifacts leading to the failure of corticospinal tract reconstruction); 4. Severe dizziness (such as nausea and vomiting) occurs during VR tasks, making it impossible to complete data collection. 5. Severe heart, liver or kidney diseases or malignant tumors (affecting data stability and follow-up).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Head MRI DTI Data;VR Trajectory Quantification Metrics; | — |
Countries
China
Contacts
Public ContactWang Yaqun
Zhejiang Provincial Tongde Hospital
Outcome results
None listed