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The efficacy and safety of neurectomy surgery and acupuncture of sphenopalatine ganglion in Allergic rhinitis

The efficacy and safety of neurectomy surgery and acupuncture of sphenopalatine ganglion in Allergic rhinitis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111543
Enrollment
Unknown
Registered
2025-11-03
Start date
2023-03-22
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis

Interventions

Control group:Posterior Nasal Nerve Ablation Technology
Treatment group:Complete transection of sphenopalatine neurovascular bundle

Sponsors

The Third Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients voluntarily participate in the trial and sign an informed consent form; 2. Patients are 18-65 years old, in line with the diagnostic criteria for Allergic rhinitis; 3. Patients with poor efficacy of standardized drug treatment; 4. Patients are not willing to undergo specific immunotherapy or poor effectiveness of specific immunotherapy; 5. Patients are not willing to undergo medication treatment; 6. Patients are willing to undergo surgical treatment; 7. Patients are able to communicate well with researchers and comply with the entire experimental requirements.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to sign an informed consent form to participate in the trial; 2. Patients under 18 years old or over 66 years old; 3. Patients with uncontrolled or acute exacerbation of asthma; 4. Patients with mental and psychological disorders; 5. Patients with severe systemic diseases; 6. Patients with Nasal polyp; 7. Patients whouse systemic steroid within the past month, and use local nasal steriod during the perioperative period; 8. Patients with unreasonable treatment effect requirements or poor compliance.

Design outcomes

Primary

MeasureTime frame
Rhinoconjunctivitis Quality of Life Questionnaire;nose/eye symptom score (total symptom score TNSS/VAS scale);

Secondary

MeasureTime frame
Adverse reactions and events;Blood routine and cytokines;Nasal resistance;

Countries

China

Contacts

Public ContactYang Qintai

The Third Affiliated Hospital of Sun Yat-sen University

yang.qt@163.com+86 20 85252239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026