iliotibial band syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Phase 1: ITBS Patients: 1. Meeting the diagnostic criteria for iliotibial band friction syndrome (ITBS) (lateral knee pain + positive Ober test + positive Noble compression test); 2. VAS score for lateral knee pain >=4 at rest or during exercise (lasting >=2 weeks); 3. Age 18-55 years old; 4. BMI 18-30 kg/m^2; 5. Forced to reduce exercise volume due to ITBS symptoms in the past month. Running Enthusiasts: 1. Regular exercise habit (running 2-3 times/week for >=6 months, weekly running distance >=30 kilometers, stable pace 5-6 min/km); 2. No history of ITBS (no lateral knee pain, tenderness or functional limitation); 3. Age 18-55 years old; 4. BMI 18-30 kg/m^2. Phase 2: ITBS Patients: 1. Clear exercise history such as running, cycling, etc., and reduced exercise volume due to pain in the past 2 weeks; Clinical manifestations: Unilateral lateral knee pain (VAS >= 4), pain intensifies when knee flexed at 30°; Physical examination: Tenderness at the lateral femoral condyle (+), modified Noble test (+), Ober test (+). 2. Good compliance, voluntarily participating in this study. 3. Age 18-55 years old, BMI 18-30kg/m^2, normal lower limb force line (Q angle < 10° for men, < 15° for women).
Exclusion criteria
Exclusion criteria: Phase 1: ITBS Patients and Running Enthusiasts: 1. Lower limb structural/functional abnormalities (e.g., congenital/ acquired deformities such as genu varum/ valgus, leg length discrepancy >1 cm); 2. Foot malalignment (pes planus or cavus: arch index 0.26); 3. History of other knee injuries (e.g., ligament tear, meniscus injury, chondral lesion); 4. Systemic confounding conditions (e.g., stroke, rheumatoid arthritis, osteoporosis); 5. Presence of metal implants; 6. Claustrophobia or MRI contraindications; 7. Recent interventions (knee surgery or corticosteroid injection within the past 3 months; ITB-specific physical therapy within the past month). Phase 2: ITBS Patients: 1. Poor compliance, unreachable, or unable to complete follow-up; 2. Comorbidities: osteoarthritis, patellofemoral pain syndrome, rheumatoid arthritis, lumbar radiculopathy, sarcoidosis, acromegaly; 3. Cognitive impairment, psychiatric disorders, or current use of psychotropic medications; 4. Recent medication/injections: NSAIDs within 72 hours; knee injections (corticosteroids/PRP) within 4 weeks; 5. Local skin infection or ulceration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensification distance;Iliotibial Band Stress Suppression Rate;Contact Pressure at the Lateral Femoral Epicondyle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak value of hip adduction angle;Delayed activation of the lateral thigh muscle;Iliotibial band thickness; | — |
Countries
China
Contacts
Shanghai General Hospital