Hashimoto's thyroiditis
Conditions
Interventions
Patients with advanced Hashimoto thyroiditis group:None
Patients with thyroid disease without Hashimoto thyroiditis group:None
Patients with stable Hashimoto thyroiditis group:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Voluntarily sign the informed consent form; 2.Age 18 years and older (inclusive), both men and women; 3.ECOG score: 0~1 points; 4.Patients treated surgically for benign/malignant thyroid disease were grouped according to their presence or absence of HT and HT stage;
Exclusion criteria
Exclusion criteria: 1.Patients with other infections; 2.Patients with other underlying diseases affecting immunity (such as HIV, active autoimmune disease, long-term immunosuppressant use, etc.); 3.Judged by the investigator to be unsuitable for participation in this study;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Molecular expression of immune checkpoints;Activity of key inflammatory pathways; | — |
Primary
| Measure | Time frame |
|---|---|
| Immune cell composition and spatial distribution; | — |
Countries
China
Contacts
Public ContactWeisheng Chen
Southern Medical University Southern Hospital
Outcome results
None listed