Diabetes
Conditions
Interventions
Moderate-Carbohydrate/High Omega-3 Group:Moderate-carbohydrate diet (CHO:PRO:FAT = 40%:30%:30%), 6 fish oil capsules per day.
Moderate-Carbohydrate/Low Omega-3 Group:Moderate-carbohydrate diet (CHO:PRO:FAT = 40%:30%:30%), 6 corn oil capsules per day.
High-Carbohydrate/Low Omega-3 Group:High-carbohydrate diet (CHO:PRO:FAT = 55%:15%:30%), 6 corn oil capsules per day.
Sponsors
Longgang Central Hospital of Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients newly diagnosed with type 2 diabetes within 3 months; 2. Glycated hemoglobin is between 6.5% and 7.5%. 3. Age between 18 and 60 years old; 4.BMI (kg/m^2) is between 18.5 and 23.9. 5. Systolic blood pressure: 90-120mmHg, diastolic blood pressure: 60-90 MMHG. 6. Good compliance, able to cooperate with research investigations, adhere to standardized nutrition management and sign informed consent forms; 7. The medication situation remained basically stable during the intervention period. 8. No n-3 PUFA-related products have been used.
Exclusion criteria
Exclusion criteria: 1.Subjects who were unwilling to continue participating in this study; 2. Subjectively unable to adhere to the intervention plan, or monitoring subjects who did not implement the intervention plan through biomarkers; 3. Subjects who experienced adverse reactions..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;Postprandial blood glucose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycated hemoglobin;Insulin;C-peptide;Total cholesterol;Total triglycerides;Low-Density Lipoprotein Cholesterol (LDL-C);High-Density Lipoprotein Cholesterol (HDL-C);Creatinine;Urea;Estimated glomerular filtration rate;Uric acid;Alanine Aminotransferase (ALT);Aspartate Aminotransferase (AST);Albumin;Prealbumin;Interleukin-6 (IL-6);Tumor Necrosis Factor-alpha (TNF-a);C-reactive protein (CRP);Procalcitonin (PCT);Body composition analysis;Fatty acids profile and metabolites (n-3, n-6 PUFA, etc.); | — |
Countries
China
Contacts
Public ContactWang Bin
Longgang Central Hospital of Shenzhen
Outcome results
None listed