Esophageal cancer
Conditions
Interventions
A1 group:Postoperative PCIA anrikefon 0.3µg/kg
A2 group:Postoperative PCIA anrikefon 0.6µg/kg
Sponsors
Anhui Provincial Cancer Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age: 65 years old to 80 years old, gender not limited. 2.ASA classification: Grade II - III. 3.BMI: 18-30 kg/m^2. 4. Expected moderate to severe postoperative pain (NRS>=4). 5. The patient or their family members can understand the research content, voluntarily sign the informed consent form, and are willing to abide by the requirements of the trial protocol.
Exclusion criteria
Exclusion criteria: 1.Those who are allergic to or contraindicated to benzodiazepines, opioids, cyclopofol, flumaciclib, naloxone, amreliphine and their drug components. 2. Patients with severe heart, lung or kidney insufficiency, combined with multiple chronic diseases, who cannot tolerate surgical anesthesia. 3. Those with a history of alcohol abuse, opioid allergy or abuse of such drugs. 4. Other circumstances that the researcher deems unsuitable for enrollment. 5. Patients who have had neurological diseases or undergone surgery recently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in resting/motor pain intensity within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| First time to remedy analgesia;Total opioid consumption;Postoperative recovery indicators;Security indicators; | — |
Countries
China
Contacts
Public ContactChaoliang Tang
Anhui Provincial Cancer Hospital
Outcome results
None listed