Prostate cancer
Conditions
Interventions
Non-prostate cancer group (benign prostate conditions or no disease):None
Prostate cancer group (diagnosed with early-stage prostate cancer):None
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old, male; 2.Patients who are scheduled to undergo prostate biopsy due to prostate cancer screening (such as elevated PSA, abnormal digital rectal examination or suspicious imaging indications); 3.Complete clinical data were available before the operation, including serum prostate-specific antigen (PSA), free PSA ratio, prostate volume, and DRE examination records; 4.Has undergone multimodal imaging examinations (such as mpMRI, ultrasound elastography, etc.) and has clear image data; 5.Agree to collect samples such as blood and urine for molecular marker detection; 6.Have the ability to sign informed consent and voluntarily participate in this study;
Exclusion criteria
Exclusion criteria: 1.Those who have been clearly diagnosed with advanced or metastatic prostate cancer; 2.Previously received prostate cancer-related treatments (such as endocrine therapy, radiotherapy, surgery, etc.); 3.Patients with severe organ dysfunction, immune diseases or mental disorders, etc., who are not suitable for participating in the study; 4.Those whose imaging data or biological samples cannot be obtained, or whose information is incomplete; 5.Patients who are unwilling or unable to cooperate to complete the research follow-up and data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The predictive performance of multimodal joint models;The diagnosis rate of early prostate cancer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive biopsy cores and tumor burden;Correlation between imaging features and pathological grading; | — |
Countries
China
Contacts
Public ContactQi Zhang
Zhejiang Provincial People's Hospital
Outcome results
None listed